I was thinking: We really need a new word that means everything. That used to be the word “universe” — it was a word specifically made to mean “everything there is” but now there’s talk of multiple universes so the word has lost its purpose. I want a word that means all there is or ever will be — whether we know of it or not or could ever possibly comprehend it. I.e., “No matter how much science advances, the extend of its knowledge will only cover an infinitesimal of the [blank].”
Don’t have a suggestion yet, but I’ll work on it. Just really seems like a word our language needs and is missing.