[High Praise! to Moe Lane]

Bravely fighting the namby-pamby conservationist menace since 1977.
I suppose Animal would make a decent Hulk.
Anyway, go ahead and offer your Muppet Superhero suggestions in the comments.
Oh… and Crazy Harry as The Green Goblin.

Wow…I don’t know enough about the Muppets to offer anything except Miss Piggy as a female version of…Wonder Warthog. Oh, and Kermit the Frog as the Green Lantern!
Statler and Waldorf both look and act like Harry and Nancy. Barney Frank would be played by Oscar the Grouch.
What this country needs is more Fozzie Bear and Cookie Monster, sadly Boehner and McConnel don’t have the right stuff.
Some came to mind. Focusing on Marvel heroes.
Kermit – Spider-Man
Miss Piggy – Mary Jane
Lew Zealand – Tony Stark
Beaker – Dr. Banner
Thig – The Hulk
Scooter – Rick Jones
Link Hogthrob – Thor
Gonzo – Daredevil
Fozie – Thing
Wayne & Wanda – Vision & Scalet Witch
Animal – Wolverine
Crazy Harry – Gambit
Prolly more fun to cast villians.
@3 – Bacon to you for Link Hogthrob as Thor. The smug narcissism is too perfect.
Also, I’m awarding you an Obscury for knowing who Thig is. And more bacon for leaving a reference link.
For everyone else, “The Great Santa Claus Switch” is viewable in 6 parts at YouTube:
http://www.youtube.com/results?search_query=The+Great+Santa+Claus+Switch
@3 Apostic, I’ve got to second what Harvey says. Impressive muppetlore there! Double-plus bacon from me.